Cell-cycle inhibition by Helicobacter pylori L-asparaginase.
Helicobacter pylori (H.pylori) is a major human pathogen causing chronic gastritis, peptic ulcer, gastric cancer, and mucosa-associated lymphoid tissue lymphoma.One of the mechanisms whereby it induces damage depends on its interference with proliferation of host tissues.We here describe the discovery of a novel bacterial factor able to inhibit the